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Product Name | BECN1, 1-450aa, Human, His tag, E.coli |
Description | Purity: > 85% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.5) containing 0.1M NaCl, 10% glycerol,1mM DTT . BECN1, also as known as Beclin-1 and autophagy-related gene (Atg) 6, belongs to the beclin family. This protein plays a central role in autophagy. Beclin-1 and its binding partner class III phosphoinositide 3-kinase (PI3K), also named Vps34, are required for the initiation of the formation of the autophagasome in autophagy. Also it required for the abcission step of cytokinesis. BECN1 plays a role in antiviral host defense. Recombinant human BECN1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional column chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. |
Size | 100ug, 20ug, 4ug |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | beclin 1, ATG6, beclin1, VPS30 |
Gene, Accession, CAS # | NP 003757 |
Catalog # | ATGP1816 |
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Order / More Info | BECN1, 1-450aa, Human, His tag, E.coli from ATGen |
Product Specific References | n/a |
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