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Product Name | GSK-2118436 mesylate |
Description | GSK2118436 is a selective BRAF V600E inhibitor. GSK2118436 binds to Raf family kinases and inhibits their activity. It is highly selective against B-Raf V600E with IC50 of 0.8 nM, compared to wild type B-Raf and c-Raf with IC50s of 3.2 nM and 5.0 nM, respectively. MW: 615.67. Purity ≥98% by HPLC |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-[3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide, methanesulfonic acid; Dabrafenib Mesylate |
Gene, Accession, CAS # | CAS: 1195768-06-9 |
Catalog # | 2800-25 |
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Order / More Info | GSK-2118436 mesylate from BIOVISION, INC. |
Product Specific References | n/a |
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