| 产品详情 |
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| Product Name | CA-074 |
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| Description | A selective cathepsin B inhibitor (Kis = 0.0087, 75, and 233 µM for rat cathepsin B, H, and L, respectively); inhibits degradation of DQ-collagen IV and DQ-collagen I in 4T1.2 breast cancer cells; reduces the number of lung and bone metastasis in a 4T1.2 mouse xenograft model at 50 mg/kg; reduces mercury-induced increases in expression of TNF-α, IL-1β, and the inflammasome component NRLP3 and decreases the severity of mercury-induced skin induration in mice at 0.1 and 0.2 mg/kg; reduces ischemia-induced hippocampal neuron cell death in monkeys |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CA074 74 TNFα IL1β NRLP-3 |
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| Gene, Accession, CAS # | CAS: 134448-10-5 |
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| Catalog # | 24679-1 |
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| Order / More Info | CA-074 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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