| 产品详情 |
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| Product Name | Cabazitaxel |
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| Description | A semisynthetic taxane; stabilizes microtubule assembly by reducing lag time for tubulin assembly (LT50 = 100 nM) and the rate of cold-induced microtubule depolymerization (IC50 = 100-250 nM) in vitro; has antiproliferative effects comparable to docetaxel in cell lines sensitive to chemotherapy (IC50s = 4-41 and 8-79 nM, respectively); more potent than docetaxel in P-glycoprotein-expressing cell lines with in vitro acquired resistance to taxanes or other chemotherapeutic agents (IC50s = 13-410.4 and 170-4,010 nM, respectively); has antitumor activity against docetaxel-susceptible human gastric carcinoma N87 and docetaxel-resistant B16/TXT melanoma xenografts, |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 890654-44-1 jevtana TXD258 XRP6258 XRP-6258 anti-proliferative anti-tumor N-87 B-16 TXD-258 semi-synthetic B16TXT |
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| Gene, Accession, CAS # | CAS: 183133-96-2 |
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| Catalog # | 22262-10 |
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| Price | |
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| Order / More Info | Cabazitaxel from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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