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Product Name | Cabazitaxel |
Description | Purity ≥98% by HPLC, MW: 835.93. Cabazitaxel is a second generation semisynthetic taxane derived from 10-deacetylbaccatin with potent anticancer activity. Cabazitaxel binds to and stabilizes tubulin, resulting in the inhibition of microtubule depolymerization and cell division, cell cycle arrest in the G2/M phase, and the inhibition of tumor cell proliferation. Cabazitaxel is more potent than docetaxel (Cat. No. 2232) in P-glycoprotein-expressing cell lines with in vitro acquired resistance to taxanes or other chemotherapeutic agents. |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | RPR116258A, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-3-phenylpropanoyl)oxy)-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate., XRP6258, TXD-258 |
Gene, Accession, CAS # | CAS: 183133-96-2 |
Catalog # | B2399-25 |
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Order / More Info | Cabazitaxel from BIOVISION, INC. |
Product Specific References | n/a |
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