| 产品详情 |
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| Product Name | [D-Arg1,D-Phe5,D-Trp7,9,Leu11]Substance P (trifluoroacetate salt) |
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| Description | A broad-spectrum neuropeptide antagonist with anticancer activity; analog of substance P; blocks intracellular calcium increases induced by vasopressin, bradykinin, gastrin, and galanin in H-510 SCLC cells; blocks vasopressin- and bradykinin-induced MAPK signaling in H-510 SCLC cells in a concentration-dependent manner; inhibits DNA synthesis in a panel of cancer cell lines (IC50s = 20-50 µM); reduces colony formation of HC12, ICR-SC112, HX149, and NCI-H226 cancer cells in vitro (IC50s = 0.5-6.5 µM); inhibits tumor growth in HC12 and ICR-SC112 SCLC mouse xenograft models (2.1 µg, s.c.) , |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | D-Phe5SP|L-756,867|SPD-D |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 24829-1 |
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| Price | |
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| Order / More Info | [D-Arg1,D-Phe5,D-Trp7,9,Leu11]Substance P (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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