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Product Name | Omalizumab ELISA (mAb-based) ELISA Assay Kit |
Description | The ImmunoGuide Omalizumab ELISA is a sandwich-type ELISA. Standards and diluted samples (serum or plasma) are incubated in the microtiter plate coated with human IgE. After incubation, the wells are washed. A horseradish peroxidase (HRP)-conjugated anti-human IgG monoclonal antibody is added and binds to the Fc part of Omalizumab pre-captured by the human IgE coated on the surface of the wells. Following incubation, the wells are washed and the bound enzymatic activity is detected by addition of chromogen-substrate. The colour developed is proportional to the amount of Omalizumab in the sample or standard. Results of samples are determined directly by using the standard curve. Sample Types: serum, plasma. Range: 3 - 100 ng/mL. Sensitivity: 1 ng/mL. Time: 2 hours • The drug Omalizumab (trade name Xolair®) is a recombinant DNA-derived humanized IgG1κ monoclonal antibody and it binds to human immunoglobulin E (IgE). The molecular weight of Omalizumab is 149 kilodaltons and is produced by a Chinese hamster ovary cell suspension culture. Omalizumab inhibits the binding of IgE to IgE receptor (FcεRI) on the surface of mast cells and basophils. Therefore, the Omalizumab is expected to limit the degree of release of mediators of the allergic response from the FcεRI bearing cells. |
Size | 1 x 96 well |
Concentration | n/a |
Applications | RUO |
Other Names | anti-drug antibody kits, anti drug shikari shakari free ELISA Assay Kit EIA, Immunoassay,Omlizumab, Xolair |
Gene, Accession, CAS # | n/a |
Catalog # | IG-AB111 |
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Order / More Info | Omalizumab ELISA (mAb-based) ELISA Assay Kit from EAGLE BIOSCIENCES INC. |
Product Specific References | n/a |
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