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| Product Name | HSBP1, human recombinant |
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| Description | The heat-shock response is elicited by exposure of cells to thermal and chemical stress and through the activation of HSFs (heat shock factors) results in the elevated expression of heat-shock induced genes. Heat shock factor binding protein-1 (HSBP1), is a 76-amino-acid protein that binds to heat shock factor 1(HSF1), which is a transcription factor involved in the HS response. During HS response, HSF1 undergoes conformational transition from an inert non-DNA-binding monomer to active functional trimers. HSBP1 is nuclear-localized and interacts with the active trimeric state of HSF1 to negatively regulate HSF1 DNA-binding activity. Overexpression of HSBP1 in mammalian cells represses the transactivation activity of HSF1. When overexpressed |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | NPC-A-13, HSBP1, Heat shock factor-binding protein 1, Nasopharyngeal carcinoma-associated antigen 13, HSF1BP, DKFZp686D1664, DKFZp686O24200 |
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| Gene, Accession, CAS # | HSBP1, Gene ID: 3281, Accession: O75506 |
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| Catalog # | 4906-25 |
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| Price | |
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| Order / More Info | HSBP1, human recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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