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Antigenic Specificity | Zyxin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:30, Western Blot: 1:250 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Zyxin Polyclonal Antibody. Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organizatio |
Immunogen | n/a |
Other Names | ZYX; zyxin; ESP-2; HED-2 |
Gene, Accession # | Entrez: 7791; Uniprot: Q15942 |
Catalog # | PA5-67603 |
Price | |
Order / More Info | Zyxin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |