产品详情 |
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Antigenic Specificity | PTPRN2 |
Clone | 8E12 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: Assay-Dependent, Western Blot: 1-5 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PTPRN2 Monoclonal Antibody (8E12). The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have |
Immunogen | n/a |
Other Names | IA-2beta, IAR, ICAAR, PTPRP |
Gene, Accession # | Entrez: 5799; Uniprot: Q92932 |
Catalog # | MA5-19759 |
Price | |
Order / More Info | PTPRN2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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