产品详情 |
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Antigenic Specificity | PTRF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 5 µg/mL, Western Blot: 0.5-1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PTRF Polyclonal Antibody. The polymerase I and transcript release factor (PTRF) enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts, regulating rRNA transcription by promoting the dissociation of transcription complexes and the re-initiation of polymerase I on nascent rRNA transcripts. PTRF also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins, translocating from caveolae to the cytoplasm after insulin stimulation. PTRF is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipo |
Immunogen | n/a |
Other Names | PTRF, Polymerase I and transcript release factor, FKSG13, CAVIN, CAVIN1, CGL4, cavin-1, TTF-I interacting peptide 12 |
Gene, Accession # | Entrez: 284119; Uniprot: Q6NZI2 |
Catalog # | PA5-34522 |
Price | |
Order / More Info | PTRF Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 27168348 |
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