产品名称 PTRH2/BIT1 Antibody from INVITROGEN ANTIBODIES
产品货号 A305-224A
产品价格 现货询价,电话:010-67529703
产品规格 100 µL
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityPTRH2/BIT1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size100 µL
Concentrationn/a
ApplicationsWestern Blot: 1:2,000-1:10,000
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DescriptionPTRH2/BIT1 Polyclonal Antibody. Adhesion to extracellular matrix regulates cell survival through both integrin engagement and appropriate cell spreading. Anoikis is the molecular mechanism of apoptosis induced by integrin detachment. Bit1 (Bcl-2 inhibitor of transcription 1) was recently identified as being involved in this process. Bit1 is a mitochondrial protein that is released into the cytoplasm upon onset of apoptosis where it forms a complex with AES, a small Groucho/transducin-like enhancer of split (TLE) protein and induces caspase-independent apoptosis. Both AES and TLE proteins are transcriptional co-repressors that play important roles in neurogenesis, segmentation, and sex determination. It has been suggested that Bit1-AES compl
Immunogenn/a
Other NamesOTTHUMP00000205936; PTH 2; bcl-2 inhibitor of transcription 1; peptidyl-tRNA hydrolase 2, mitochondrial
Gene, Accession #Entrez: 51651; Uniprot: Q9Y3E5
Catalog #A305-224A
Price
Order / More InfoPTRH2/BIT1 Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
产品资料