| 产品详情 |
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| Antigenic Specificity | PTS |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50-1:200, Western Blot: 1:500-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PTS Polyclonal Antibody. The tetrahydrobiopterin (BH4) cofactor is essential for hepatic hydroxylase, which is involved in phenylalanine degradation and catecholamine and serotonin biosynthesis. BH4 is also an essential and limiting cofactor for all types of nitric oxide synthase. BH4 deficiency results in hyperphenylalaninemia and monoamine neurotransmitter depletion and is most commonly due to autosomal recessive mutation in 6-pyruvoyltetrahydropterin synthase (PTPS), the second enzyme for BH4 biosynthesis. The active site of PTPS consists of the pterin-anchoring Glu A107 neighbored by two catalytic motifs: a Zn(II) binding site and an inter-subunit catalytic triad formed by Cys A42, Asp B88 and His B89. The active site of PTPS undergoes |
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| Immunogen | n/a |
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| Other Names | 6-pyruvoyl tetrahydrobiopterin synthase; PTP synthase; PTPS; PTS |
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| Gene, Accession # | Entrez: 19286, 29498, 5805; Uniprot: P27213, Q03393, Q9R1Z7 |
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| Catalog # | PA5-76904 |
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| Price | |
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| Order / More Info | PTS Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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