| 产品详情 |
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| Antigenic Specificity | ZRANB3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | bovine, canine, equine, human, porcine |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Western Blot: 1.0 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ZRANB3 Polyclonal Antibody. DNA annealing helicase and endonuclease required to maintain genome stability at stalled or collapsed replication forks by facilitating fork restart and limiting inappropriate recombination that could occur during template switching events. Recruited to the sites of stalled DNA replication by polyubiquitinated PCNA and acts as a structure-specific endonuclease that cleaves the replication fork D-loop intermediate, generating an accessible 3'-OH group in the template of the leading strand, which is amenable to extension by DNA polymerase. In addition to endonuclease activity, also catalyzes the fork regression via annealing helicase activity in order to prevent disintegration of the replication fork and the format |
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| Immunogen | n/a |
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| Other Names | 4933425L19Rik; AH2; DNA annealing helicase and endonuclease ZRANB3; annealing helicase 2; zinc finger Ran-binding domain-containing protein 3; zinc finger, RAN-binding domain containing 3 |
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| Gene, Accession # | Entrez: 100050746, 100157618, 476128, 529922, 84083; Uniprot: E1BB03, Q5FWF4 |
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| Catalog # | PA5-71320 |
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| Price | |
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| Order / More Info | ZRANB3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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