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Product Name | Recombinant Rat IL17 / IL17a Protein |
Description | Purity >95% as determined by SDS-PAGE. Interleukin 17A (IL-17A), also known as CTLA-8, is a member of the IL-17 family of proteins. IL-17A is proinflammatory cytokine that is secreted by activated CD4+ and CD8+ T lymphocytes. IL-17A acts through its receptor, IL-17R, to promote increased cytokine and chemokine secretion. In turn, the cytokines and chemokines mediate the immunoregulatory function of IL-17A by promoting the proliferation, maturation, and chemoattraction of neutrophils to inflammatory sites. Elevated levels of IL-17A are associated with rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer, and multiple sclerosis. Human, mouse, and rat IL-17A show activity on mouse cells. |
Size | 5ug, 25ug, 100ug, 500ug, 1mg |
Concentration | n/a |
Applications | Bioactive |
Other Names | IL17, IL17A, CTLA-8, IL-17A, CTLA8, IL-17, IL17 |
Gene, Accession, CAS # | IL17A, Gene ID: 301289, UniProt: Q61453 |
Catalog # | QP5511-5ug |
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Order / More Info | Recombinant Rat IL17 / IL17a Protein from ENQUIRE BIOREAGENTS |
Product Specific References | n/a |
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