产品名称 FRAX597 from BIOVISION, INC.
产品货号 B1890-5
产品价格 现货询价,电话:010-67529703
产品规格 5 mg
产品品牌 BIOVISION, INC.
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Product NameFRAX597
DescriptionFRAX597 is a potent group I PAK (p21-activated kinase) inhibitor (IC50 values are 8, 13 and 19 nM for PAK1, 2 and 3, respectively). Displays significant inhibition of YES1, RET, CSF1R and TEK at 100 nM, but is inactive against group II PAK isoforms (IC50 >10 µM for PAK4). FRAX597 inhibits the proliferation of NF2-deficient schwannoma cells in culture and displays potent anti-tumor activity in vivo. MW: 558.1. Purity ≥98% by HPLC
Size5 mg
Concentrationn/a
Applicationsn/a
Other Names6-[2-Chloro-4-(5-thiazolyl)phenyl]-8-ethyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7-(8H)-one
Gene, Accession, CAS #CAS: 1286739-19-2
Catalog #B1890-5
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Order / More InfoFRAX597 from BIOVISION, INC.
Product Specific Referencesn/a
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