产品名称 Ornithine Decarboxylase I (ODC1) Inhibitor Screening Kit (Colorimetric) from BIOVISION, INC.
产品货号 K176-100
产品价格 现货询价,电话:010-67529703
产品规格 100 assays
产品品牌 BIOVISION, INC.
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Product NameOrnithine Decarboxylase I (ODC1) Inhibitor Screening Kit (Colorimetric)
DescriptionOrnithine decarboxylase (ODC) (EC 3.5.3.1) is a pyridoxal phosphate-dependent enzyme, which cleaves ornithine into putrescine and carbon dioxide. ODC is the initial step in the polyamine synthesis pathway. Putrescine, along with the subsequent polyamine products, spermidine and spermine has been shown to promote cell proliferation and arrest cell apoptosis in cancer. It is also known that proto-oncogenes, such as c-Myc can transcriptionally regulate this protein. Ornithine decarboxylase inhibitors, e.g. efluornithine (2-difluromethylornithine), alexidine and their analogs have been studied as ornithine and employed to irreversibly inhibit ODC and thus abolish cell growth by reducing intracellular polyamine that is required for the aforement
Size100 assays
Concentrationn/a
ApplicationsScreening for inhibitors of human Ornithine decarboxylase I (ODC1)
Other NamesODC,ornithine decarboxylase
Gene, Accession, CAS #n/a
Catalog #K176-100
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Order / More InfoOrnithine Decarboxylase I (ODC1) Inhibitor Screening Kit (Colorimetric) from BIOVISION, INC.
Product Specific Referencesn/a
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