| 产品详情 |
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| Product Name | LGK974 |
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| Description | LGK-974 is a potent and specific inhibitor of Porcupine (porcn), a Wnt-specific acyltransferase (IC50 = ~0.4 nM). GK974 potently inhibits Wnt signaling, has strong efficacy in rodent tumor models, and is well-tolerated. In addition, head and neck cancer cell lines with loss-of-function mutations in the Notch signaling pathway have a high response rate to LGK974. MW: 396.44. Purity ≥98% by HPLC |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-(2',3-dimethyl-[2,4'-bipyridin]-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide |
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| Gene, Accession, CAS # | CAS: 1243244-14-5 |
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| Catalog # | 2645-1 |
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| Price | |
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| Order / More Info | LGK974 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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