| 产品详情 |
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| Antigenic Specificity | NFKB p65, C-terminus |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | delipidated & defibrinated |
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| Size | 100 µL |
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| Concentration | 80 mg/mL |
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| Applications | ELISA, Gel Shift, Immunohistochemistry, Western Blot. Anti-NFkB p65 (Rel A) is suitable for the detection by immunoblot of human and mouse NFkB p65 (Rel A), immunohistochemistry, and ELISA. This product was also tested in a gel supershift assay and found to be reactive against all p65 (Rel A) containing human, mouse or rat NFkB complexes using 0.5 to 1.0 µl per assay. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NFkB p65 (Rel A) was prepared from monospecific antiserum by delipidation and defibrination. Anti-NFkB p65 (Rel A) may react non-specifically with other proteins. Control peptide (code #100-4165p) will compete only with the specific reaction of antiserum with the NFkB p65 (Rel A) subunit. |
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| Immunogen | NFkB p65 (Rel A) peptide corresponding to a region near the C-terminus of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH). |
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| Other Names | rabbit Anti-NFKB p65 antibody, rabbit Anti-Rel A antibody, NFKB, nfkb, NF-kB, NF-kappaB, NFkappaB, Nuclear factor NF-kappa-B p65 subunit |
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| Gene, Accession # | RELA, Gene ID: 5970, NCBI: 223468676, UniProt: Q04206 |
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| Catalog # | 100-4165 |
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| Price | |
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| Order / More Info | NFKB p65, C-terminus Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
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| Product Specific References | Unlap, M.T. and Jope, R.S. (1997). Dexamethasone attenuates NF-?B DNA binding activity without inducing I?B levels in rat brain in vivo. Molecular Brain Research 45: 83-89.Poser, I., Golob, M., Buettner, R. and Bosserhoff, A.K. (2003) Upregulation of HMG1 Leads to Melanoma Inhibitory Activity Expression in Malignant Melanoma Cells and Contributes to Their Malignancy Phenotype. Mol. Cell Biol. 23(8): 2991-2998.Ghosh M, Yang Y, Rothstein JD, Robinson MB. Nuclear factor-?B contributes to neuron-dependent induction of glutamate transporter-1 expression in astrocytes. J. Neurosci. 2011 Jun 22;31(25):9159-9169. Jobin, C, et al. (1999) Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity. J. Immunol. 163(6): 3474-3483.Cao S, Zhang X, Edwards JP, Mosser DM. (2006 ) NF-kappaB1 (p50) homodimers differentially regulate pro- and anti-inflammatory cytokines in macrophages. J. Biol. Chem. 2006 Sep 8;281(36):26041-26050. Lou H, Kaplowitz N. (2007 ) Glutathione depletion down-regulates tumor necrosis factor alpha-induced NF-kappaB activity via IkappaB kinase-dependent and -independent mechanisms. J. Biol. Chem. 2007 Oct 5;282(40):29470-29481. Yoon C, Korade Z, Carter BD.(2008) Protein kinase A-induced phosphorylation of the p65 subunit of nuclear factor-kappaB promotes Schwann cell differentiation into a myelinating phenotype. J. Neurosci. 2008 Apr 2;28(14):3738-3746.Begley LA, Kasina S, Mehra R, et al. (2008) CXCL5 promotes prostate cancer progression. Neoplasia. 2008 Mar;10(3):244-254.Limpert Allison S. ; Carter BD. (2010) Axonal Neuregulin 1 Type III Activates NF-kappa B in Schwann Cells during Myelin Formation. Journal Biological Chemistry 285 (22): 16614-16622 DOI: 10.1074/jbc.M109.098780 Published: MAY 28 2010 |
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