| 产品详情 |
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| Product Name | ARV-825 |
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| Description | ARV-825 is a BRD4 inhibitor. It is a hetero-bifunctional PROTAC (Proteolysis Targeting Chimera) that recruits BRD4 to the E3 ubiquitin ligase cereblon, leading to fast, efficient, and prolonged degradation of BRD4. ARV-825 more effectively suppresses c-MYC levels and downstream signaling than small-molecule BRD4 inhibitors, resulting in more effective cell proliferation inhibition and apoptosis induction in Burkitt's lymphoma (BL). MW: 941.4. Purity ≥98% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-(2-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethoxy)ethoxy)phenyl)acetamide |
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| Gene, Accession, CAS # | CAS: 1818885-28-7 |
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| Catalog # | B2019-5 |
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| Price | |
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| Order / More Info | ARV-825 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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