| 产品详情 |
| Edit |   |
|---|
| Product Name | WM75 Viable Cells (5 x10^6 cells) |
|---|
| Description | WM75 is a metastatic human melanoma cell line that displays pigmented morphology. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. This cell line expresses wild type PTEN, N-RAS, c-KIT, and CDK4 genes. WM75 cells produce xenograft tumors when injected into immunocompromised mice. |
|---|
| Size | 1 mL |
|---|
| Concentration | 5.0 million cells/ml |
|---|
| Applications | The key applications of these cell lines include genetic studies, xenograft production, drug testing, and drug target discovery. These cell line models can be used in various biological assays, and for identifying critical target genes, and cell signaling pathways. |
|---|
| Other Names | Human Melanoma, patient derived tumor, tumor models, skin cancer, xenograft |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | WM75-01-0005 |
|---|
| Price | |
|---|
| Order / More Info | WM75 Viable Cells (5 x10^6 cells) from ROCKLAND IMMUNOCHEMICALS INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|