产品名称 WM4002 Viable Cells (10 x10^6 cells) from ROCKLAND IMMUNOCHEMICALS INC.
产品货号 WM4002-01-0010
产品价格 现货询价,电话:010-67529703
产品规格 1 mL
产品品牌 ROCKLAND IMMUNOCHEMICALS INC.
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Product NameWM4002 Viable Cells (10 x10^6 cells)
DescriptionWM4002 is a metastatic human melanoma cell line. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. This cell line also expresses PTEN loss of function including hemizygous deletion and is wild type for N-RAS, c-KIT, and CDK4 genes. WM4002 cells produce xenograft tumors when injected into immunocompromised mice.
Size1 mL
Concentration10.0 million cells/ml
ApplicationsThe key applications of these cell lines include genetic studies, xenograft production, drug testing, and drug target discovery. These cell line models can be used in various biological assays, and for identifying critical target genes, and cell signaling pathways.
Other NamesHuman Melanoma, patient derived tumor, tumor models, skin cancer, xenograft
Gene, Accession, CAS #n/a
Catalog #WM4002-01-0010
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Order / More InfoWM4002 Viable Cells (10 x10^6 cells) from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
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