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Product Name | Phospholipase D (PLD) Activity Colorimetric Assay Kit |
Description | Phospholipase D (PLD) is a key player in phospholipid metabolism. PLD hydrolyzes the phosphodiester bond of the glycerophospholipids, resulting in the production of phosphatidic acid and a free headgroup. PLD activity regulates the actin cytoskeleton, vesicle trafficking for secretion and endocytosis, and receptor signaling. Abnormalities in PLD activity and expression have been associated with Alzheimer's disease, stroke, cancer and other brain disorders. BioVision's Phospholipase D Activity Assay Kit provides a simple and sensitive method of measuring PLD activity using colorimetry (OD 570 nm). In this assay, PLD cleaves choline from Phosphatidylcholine. The free choline is then oxidized by PLD enzyme mix to generate an intermediate which |
Size | 100 assays |
Concentration | n/a |
Applications | • Measurement of PLD activity in various tissues/cells• Analyzing intracellular signaling• Screening of PLD inhibitors |
Other Names | Lecithinase D Activity Colorimetric Assay Kit, Choline Phosphatase Activity Colorimetric Assay Kit, Lipophosphodiesterase II Activity Colorimetric Assay Kit |
Gene, Accession, CAS # | n/a |
Catalog # | K725-100 |
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Order / More Info | Phospholipase D (PLD) Activity Colorimetric Assay Kit from BIOVISION, INC. |
Product Specific References | n/a |
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