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Product Name | Endothelin Converting Enzyme 1 Activity Assay Kit (Fluorometric) |
Description | Endothelin Converting Enzyme 1 (ECE1; EC: 3.4.24.71) is a membrane-bound metalloprotease that cleaves inactive big endothelin (big ET-1), which is the precursor of active endothelin. Studies have shown that big ET-1 could be used as a predictor of survival in patients suffering esophageal squamous cell carcinoma. ECE-1 is abundantly expressed in vivo in endothelial cells producing mature ET-1. As of today, Endothelin is the most potent vasoconstrictor known and it has cytokine- or hormone-like activities. Therefore, ECE-1 could play a significant role in pathogenesis of cardiovascular diseases and Alzheimer's Disease. BioVision's Endothelin Converting Enzyme 1 Activity Assay Kit utilizes the ability of active ECE-1 to cleave a synthetic sub |
Size | 100 assays |
Concentration | n/a |
Applications | Detection of ECE1 activity in tissue/cell lysates |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | K536-100 |
Price | |
Order / More Info | Endothelin Converting Enzyme 1 Activity Assay Kit (Fluorometric) from BIOVISION, INC. |
Product Specific References | n/a |
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