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Product Name | D-64131 |
Description | An inhibitor of tubulin polymerization (IC50 = 0.53 µM); arrests the cell cycle at the G2/M transition (IC50 = 92 nM); preferentially cytotoxic to cycling cells; has antiproliferative activity in various cancer cell lines (IC50s = 24-144 nM) and in cell lines resistant to other tubulin inhibitors (IC50s = 20-77 nM); reduces tumor growth in a mouse xenograft model of human amelanoic melanoma at doses of 200 and 400 mg/kg, |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | anti-mitotic proliferative D64131 |
Gene, Accession, CAS # | CAS: 74588-78-6 |
Catalog # | 22944-25 |
Price | |
Order / More Info | D-64131 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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