产品详情 |
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Product Name | CCT 018159 |
Description | Novel inhibitor of heat shock protein 90 (Hsp90) ATPase activity (IC50 = 5.7 μM) that displays selectivity over human Hsp72 and topoisomerase II. Inhibits proliferation of HCT116 human colon tumor cells and produces upregulation of Hsp70 and downregulation of c-Raf and cdk4. More soluble than 17-AAG (Cat. No. 1515) and is independent of NQO1/DT-diaphorase and P-glycoprotein expression. Purity 98%. MW (observed): 352.39 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 4-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-methyl-1H-pyrazol-3-yl]-6-ethyl-1,3-benzenediol |
Gene, Accession, CAS # | Gene ID: 3320, CAS: 171009-07-7 |
Catalog # | 2435/50 |
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Order / More Info | CCT 018159 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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