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| Product Name | Demethylasterriquinone B1 |
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| Description | Selective insulin receptor (IR) activator (EC50 values are 3 - 6 μM for IRTK and 100 μM for IGF1R and EGFR). Increases IR β subunit tyrosine phosphorylation and activation of PI 3-kinase and Akt, but not ERK. Induces glucose uptake in adipocytes and skeletal muscle in vitro, without enhancing vascular proliferation. Binds GAPDH. Also activates Trk by interacting at a site distinct from the neurotrophin-binding site. Purity 98%. MW (observed): 506.59 |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[2-(1,1-Dimethyl-2-propenyl)-1H-indol-3-yl]-3,6-dihydroxy-5-[7-(3-methyl-2-butenyl)-1H-indol-3-yl]-2,5-cyclohexadiene-1,4-dione. DAQ B1, L-783,281, DMAQ-B1 |
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| Gene, Accession, CAS # | CAS: 78860-34-1 |
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| Catalog # | 1819/5 |
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| Price | |
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| Order / More Info | Demethylasterriquinone B1 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 28963439 |
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| 产品资料 |
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