产品详情 |
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Product Name | Desformylflustrabromine hydrochloride |
Description | Positive allosteric modulator of nicotinic α4β2 receptors; selectively increases the ionic current through α4β2 in the presence of ACh. Displays 14.7-fold selectivity for α4β2 over homomeric (α7) receptors. Moderately cytotoxic in HCT-116 cells. Also inhibits human muscle (αβεδ) and Torpedo (αβγδ) nAChRs (IC50 values are 1.0 and 0.1 μM, respectively) by binding in the ion channel. Purity 98%. MW (observed): 357.72 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 6-Bromo-2-(1,1-dimethyl-2-propenyl)-N-1H-indole-3-ethanamine hydrochloride |
Gene, Accession, CAS # | CAS: 951322-11-5 |
Catalog # | 3328/10 |
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Order / More Info | Desformylflustrabromine hydrochloride from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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