| 产品详情 |
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| Product Name | Bosutinib |
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| Description | Dual inhibitor of Abl and Src kinases (IC50 = 1.2 nM for Src in an enzymatic assay). Displays antiproliferative activity against chronic myelogenous leukemia (CML) cells and decreases the motility and invasion of breast cancer cell lines. Also exhibits potent antiproliferative activity in anchorage-independent, Src-transformed rat fibroblasts (IC50 = 100 nM). Displays selectivity for Src over non-Src family kinases such as growth factor receptor tyrosine kinases. Purity 99%. MW (observed): 530.45 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile. SKI-606 |
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| Gene, Accession, CAS # | CAS: 380843-75-4 |
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| Catalog # | 4361/50 |
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| Price | |
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| Order / More Info | Bosutinib from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 22493660, 24292070 |
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| 产品资料 |
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