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| Product Name | bPiDDB |
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| Description | Orthosteric neuronal nicotinic acetylcholine receptor (nAChR) antagonist (IC50 values are 0.17, 0.25, 0.4, 4.8, 6.5, 8.2, 20 and 34 μM at α3β4, α1β1εδ, α3β4β3, α6β4β3, α7, α4β2, α3β2β3 and α6/3β2β3 receptors respectively). Attenuates nicotine-evoked dopamine release from the ventral tegmental area in vivo (IC50 = 0.2 nM) and reduces nicotine self-administration in rats. Brain penetrant. Purity 98%. MW (observed): 514.38 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1,1'-(1,12-Dodecanediyl)bis[3-methylpyridinium] dibromide |
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| Gene, Accession, CAS # | CAS: 525596-66-1 |
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| Catalog # | 3221/50 |
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| Order / More Info | bPiDDB from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 25716861 |
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| 产品资料 |
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