| 产品详情 |
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| Product Name | FLI-06 |
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| Description | A potent Notch signaling (EC50 = 2.3 µM) as well as the early secretory pathway inhibitor. FLI-06 leads to a disruption of the Golgi by a mechanism different from Brefeldin A (Cat. No. 1560) or other known secretion inhibitors. FLI-06 blocks secretion by inhibiting the recruitment of cargo to ER exit sites, but not the formation of COPII vesicles. FLI-06 transforms the tubular regions of the ER to large sheets, suggesting that regions of high curvature at ER exit sites are essential for the recruitment of cargo. MW: 438.52. Purity >98% by HPLC |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Cyclohexyl 1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylate |
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| Gene, Accession, CAS # | CAS: 313967-18-9 |
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| Catalog # | 2603-25 |
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| Order / More Info | FLI-06 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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