| 产品详情 |
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| Antigenic Specificity | DNMT1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µg |
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| Concentration | 0.5 mg/ml |
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| Applications | Western blot |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DNMT1 Antibody. Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting and is essential for mammalian development. Hypermethylation of CpG islands in tumor suppressor genes or hypomethylation of bulk genomic DNA may be linked with development of cancer. To date, 3 families of mammalian DNA methyltransferase genes have been identified which include Dnmt1, Dnmt2 and Dnmt3. Dnmt1 is constitutively expressed in proliferating cells and inactivation of this gene causes global demethylation of genomic DNA and embryonic lethality. |
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| Immunogen | Synthetic peptide surrounding amino acid 1208 of rat DNMT1. |
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| Other Names | DNA (cytosine-5)-methyltransferase 1, Dnmt1, CXXC-type zinc finger protein 9, DNA methyltransferase HsaI, DNA MTase HsaI, M.HsaI, MCMT |
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| Gene, Accession # | Gene ID: UniGene Rn.6955., Accession: Q9Z330 |
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| Catalog # | 3946-100 |
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| Price | |
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| Order / More Info | DNMT1 Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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