| 产品详情 |
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| Antigenic Specificity | DNMT2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µg |
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| Concentration | 0.5 mg/ml |
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| Applications | Western blot, Immunofluorescence |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Dnmt2 Antibody. Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting and is essential for mammalian development. Hypermethylation of CpG islands in tumor suppressor genes or hypomethylation of bulk genomic DNA may be linked with development of cancer. To date, 3 families of mammalian DNA methyltransferase genes have been identified which include Dnmt1, Dnmt2 and Dnmt3. Dnmt1 is constitutively expressed in proliferating cells and inactivation of this gene causes global demethylation of genomic DNA and embryonic lethality. Dnmt2 is expressed at low levels in adult tissues and its inactivation does not affect DNA methylation or maintenance of methylation. Dnmt2 contains all the se |
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| Immunogen | Synthetic peptides surrounding amino acid 42 and 364 of mouse Dnmt2 |
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| Other Names | Dnmt2 , TRDMT1 , RNMT1 , OTTHUMP00000045198 , cytosine-5-methyltransferase , EC 2.1.1.29 |
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| Gene, Accession # | Gene ID: 13434, Accession: O55055 |
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| Catalog # | 3488-100 |
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| Price | |
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| Order / More Info | DNMT2 Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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