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Product Name | Human Recombinant Cyclophilin B |
Description | Cyclophilin B is a cyclosporine-binding protein. It is both secreted and retained in the ER. When secreted, Cyclophilin B mediates chemotaxis and T cell adhesion to fibronectin. This is likely due to its prolyl cis/trans isomerase activity. Intracellularly, Cyclophilin B appears to serve as a molecular chaperone for molecules destined for secretion. It does so via stabilization, and facilitating the activity of additional chaperones. It also bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. MW: 21.2 kDa. Purity ≥95% |
Size | 100 µg |
Concentration | 1 mg/ml |
Applications | RUO |
Other Names | PPIB, Peptidyl prolyl isomerase B, CYPB; SCYLP; CYP-S1 |
Gene, Accession, CAS # | PPIB, Gene ID: 5479, Accession: P23284 |
Catalog # | 6310-100 |
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Order / More Info | Human Recombinant Cyclophilin B from BIOVISION, INC. |
Product Specific References | n/a |
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