| 产品详情 |
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| Product Name | Human Recombinant FKBP1a/FKBP12 |
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| Description | FKBP1A is part of the family of immunophilins, which have in common high affinity for immunosuppressant drugs and a peptidyl-prolyl cis-trans isomerase (PPIase). In the absence of immunosuppressive ligands, FKBP1A is involved in intracellular calcium regulation by associating with 3 types of Ca2+ release channel complexes: skeletal ryanodine receptors, cardiac ryanodine receptors and the inositol 1, 4, 5-triphosphate receptor. FKBP1A also interacts with TGF type I receptor exerting an inhibitory effect on the TGFβ-I signaling pathway. FKBP12 plays a role in modulation of ryanodine receptor isoform-1 (ryr-1), a component of the calcium release channel of skeletal muscle sarcoplasmic reticulum. FKBP1A increase the folding of proteins and |
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| Size | 100 µg |
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| Concentration | 1 mg/ml |
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| Applications | RUO |
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| Other Names | FK506 binding protein 1a, 12kDa, PPIase FKBP1A, Rotamase, FKBP1, PKC12 |
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| Gene, Accession, CAS # | FKBP1A, Gene ID: 2280, Accession: P62942 |
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| Catalog # | 6340-100 |
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| Order / More Info | Human Recombinant FKBP1a/FKBP12 from BIOVISION, INC. |
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| Product Specific References | n/a |
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