产品详情 |
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Antigenic Specificity | NTAN1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NTAN1 Polyclonal Antibody. Side-chain deamidation of N-terminal asparagine residues to aspartate. Required for the ubiquitin-dependent turnover of intracellular proteins that initiate with Met-Asn. These proteins are acetylated on the retained initiator methionine and can subsequently be modified by the removal of N-acetyl methionine by acylaminoacid hydrolase (AAH). Conversion of the resulting N-terminal asparagine to aspartate by PNAD renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. This enzyme does not act on substrates with internal or C-terminal asparagines and does not act on glutamine residues in any position. |
Immunogen | n/a |
Other Names | N-terminal asparagine amidohydrolase, PNAA, PNAD, protein N-terminal Asn amidase, protein N-terminal asparagine amidohydrolase, protein NH2-terminal asparagine amidohydrolase, protein NH2-terminal asparagine deamidase, protein NTN-amidase |
Gene, Accession # | Entrez: 123803; Uniprot: Q96AB6 |
Catalog # | PA5-31446 |
Price | |
Order / More Info | NTAN1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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