| 产品详情 |
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| Product Name | OTX015 |
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| Description | OTX015 is a potent inhibitor of BRD2, BRD3, and BRD4 (EC50s = 10-19 nM). It displays antiproliferative effects at a sub-micromolar range in vitro in a wide range of solid tumor types and leukemias, downregulating c-Myc expression and inducing cell cycle arrest and apoptosis. At 100 mg/kg, OTX015 has been shown to inhibit the growth of Ty82 BRD-NUT midline carcinoma tumors in nude mice by 79%. MW: 492. Purity ≥98% |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (6S)-?4-?(4-?chlorophenyl)-?N-?(4-?hydroxyphenyl)-?2,?3,?9-?trimethyl-?6H-?thieno[3,?2-?f][1,?2,?4]triazolo[4,?3-?a][1,?4]diazepine-?6-?acetamide; HY-15743 |
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| Gene, Accession, CAS # | CAS: 202590-98-5 |
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| Catalog # | 2651-1 |
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| Price | |
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| Order / More Info | OTX015 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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