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Product Name | Viridicatumtoxin |
Description | A mycotoxin with antimicrobial, cytotoxic, and toxic properties; inhibits the growth of B. subtilis, M. luteus, C. perfringens, B. fragilis, MRSA, C. albicans, S. cerevisiae, M. racemosus, A. niger, and P. chrysogenum (MICs = 0.39-25 µg/ml); inhibits the production of polyprenyl alcohols by S. aureus UPP synthase, E. coli OPP synthase, and S. cerevisiae DedoIPP synthase in vitro (IC50s = 3.1, 21, and 71 µM, respectively); has cytotoxic effects against human Jurkat T (IC50 = 4.92 µM), CLL (LC50 = 0.7-3.5 nM), and bone marrow-derived HS-5 stromal cells; toxic to rats and mice when administered intraperitoneally (LD50s = 80 and 90 mg/kg, respectively) and to rats when administered via gastric intubation (LD50 = 122.4 mg/kg), but not to rats or mice when administered orally or through subcutaneous injection |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | NSC 159628 |
Gene, Accession, CAS # | CAS: 39277-41-3 |
Catalog # | 25480-1 |
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Order / More Info | Viridicatumtoxin from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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