产品详情 |
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Antigenic Specificity | Cathepsin L |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 100 µg |
Concentration | 0.2 mg/ml |
Applications | Western blot, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cathepsin L Antibody. Cathepsin L is a normal lysosomal cysteine endoproteases that is expressed in all cells. The latent 39 kDa pro-Cathepsin L must be processed by cleavage of the 96 amino acid pro-peptide, to generate the active two-chain form made up of 21 and 5 kDa subunits. Mature Cathepsin L is normally localized in the lysosomes where it plays a major role in intracellular protein catabolism. The fact that Cathepsin L is also capable of degrading extracellular matrix proteins sµggests that it may play a role in invasion and metastasis and could be a useful prognostic indicator for cancer. |
Immunogen | Synthetic peptide surrounding amino acid 223 of human Cathepsin L |
Other Names | CTSL, CATL, CTSL1, MEP, EC 3.4.22.15 |
Gene, Accession # | Gene ID: 1514, Accession: P07711 |
Catalog # | 3192-100 |
Price | |
Order / More Info | Cathepsin L Antibody from BIOVISION, INC. |
Product Specific References | n/a |
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