| 产品详情 |
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| Antigenic Specificity | IRGM |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 5 µg/mL, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | IRGM Polyclonal Antibody. Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. Two of the strongest hits implicate genes IRGM and ATG16L1, which encode proteins thought to be critical to the autophagy pathway and being significantly associated with Crohn's disease. In mouse, IRGM belongs to a family of -gamma-interferon-induced GTP-binding proteins of approximately 48 kDa. Murine IRGM induces autophagy and generates large autolysosomal organelles as a mechanism for the elim |
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| Immunogen | n/a |
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| Other Names | IFI1, IRGM1, LRG-47, LRG47; LPS-stimulated RAW 264.7 macrophage protein 47 homolog; LRG-47-like protein; immunity-related GTPase family M protein; immunity-related GTPase family, M1; interferon-inducible protein 1 |
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| Gene, Accession # | Entrez: 15944, 303090, 345611; Uniprot: A1A4Y4, Q60766, Q6AYC2 |
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| Catalog # | PA5-20508 |
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| Price | |
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| Order / More Info | IRGM Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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