| 产品详情 |
| Edit |   |
|---|
| Product Name | Sunitinib Malate (Sutent) |
|---|
| Description | Sunitinib is a potent inhibitor of CSF-1 receptor kinase in an enzyme assay, with an IC50 of 7 nM, and inhibits receptor phosphorylation in a cellular assay with an IC50 of 61 nM. Sunitinib inhibits SCF-induced phosphotyrosine levels on KIT (IC50 = 1 - 10 nM) and reduced SCF-stimulated ERK1/2 phosphorylation with an IC50 value consistent with that for inhibition of KIT phosphotyrosine levels. Sunitinib also inhibited SCF-stimulated proliferation in NCI-H526 cells (IC50 = 2 nM). MW: 532.56. Purity ≥99% by HPLC |
|---|
| Size | 100 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | Sunitinib Maleate, SU-11248, Sutent, PHA-290940AD, PNU-290940AD |
|---|
| Gene, Accession, CAS # | CAS: 341031-54-7 |
|---|
| Catalog # | 1611-100 |
|---|
| Price | |
|---|
| Order / More Info | Sunitinib Malate (Sutent) from BIOVISION, INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|