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Product Name | Resveratrol |
Description | Potent SIRT1 activator and a phytoestrogen with antitumor, antioxidant, antiplatelet, anti-inflammatory and antifungal effects. Inhibits cytochrome P450 1A1 (IC50 = 23 uM) and displays mixed agonist/antagonist actions at ERalpha and ERbeta estrogen receptors. Trans-Resveratrol is a potent phenolic antioxidant found in grapes and red wine that also has antiproliferative and anti-inflammatory activity. trans-Resveratrol is also a selective inhibitor of cyclooxygenase-1 (COX-1). It inhibits COX and peroxidase activities of COX-1 with ED50 values of 15 and 3.7 uM, respectively. There is essentially no inhibition of the COX-2 activity. Resveratrol also activates sirtuins and, extends lifespan in C. elegans. Converted into the anticancer agent piceatannol by cytochrome P450 1B1. |
Size | 500 mg |
Concentration | n/a |
Applications | Activator or Inhibitor |
Other Names | SIRT 1 inhibitor |
Gene, Accession, CAS # | n/a |
Catalog # | P002-500MG |
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Order / More Info | Resveratrol from ARBOR ASSAYS, INC. |
Product Specific References | n/a |
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