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Product Name | Recombinant Mouse PDGFA Protein |
Description | Purity >95% as determined by SDS-PAGE. Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by interleukin 1 (IL-1), interleukin 6 (IL-6), tumor necrosis factor alpha (TNF?), transforming growth factor beta (TGF-?), and epidermal growth factor (EGF) signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-a and PDGFR-b. |
Size | 2ug, 10ug, 100ug, 500ug, 1mg |
Concentration | n/a |
Applications | Bioactive |
Other Names | PDGF1, PDGF-A |
Gene, Accession, CAS # | PDGFA, Gene ID: 18590, NCBI: NP_032834.1, UniProt: P20033 |
Catalog # | QP5462-2ug |
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Order / More Info | Recombinant Mouse PDGFA Protein from ENQUIRE BIOREAGENTS |
Product Specific References | n/a |
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