产品详情 |
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Antigenic Specificity | CD276 |
Clone | 6A1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 50 µl |
Concentration | n/a |
Applications | Affinity purified |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Monoclonal antibody to detect CD276 in human samples. Costimulatory B7 molecules (e.g., B7-1, or CD80; MIM 112203) signal through CD28 (MIM 186760) family molecules such as CD28, CTLA4 (MIM 123890), and ICOS (MIM 604558). May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 a |
Immunogen | Purified recombinant fragment of human CD276 expressed in E. Coli. |
Other Names | CD276 antigen, 4Ig-B7-H3, B7 homolog 3, B7-H3, Costimulatory molecule, CD276, CD276, B7H3 |
Gene, Accession # | Gene ID: 80381, Accession: Q5ZPR3 |
Catalog # | A1070-50 |
Price | |
Order / More Info | CD276 Antibody from BIOVISION, INC. |
Product Specific References | n/a |
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