产品详情 |
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Antigenic Specificity | CD86 (B7-2) |
Clone | GL1 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, kappa |
Format | allophycocyanin (APC) conjugate |
Size | 50 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.06 µg/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD86 (B7-2) Monoclonal Antibody (GL1), APC, eBioscience™. CD86 is one of two ligands (the other CD80) for CTLA4 and CD28. CD86 acts as costimulatory molecule in eliciting T-cell help during antigen presentation. Antigen presentation in the absence of sufficient co-stimulation involving CD86/CD80 can induce tolerance. CD80 appears to play a role distinct from CD80 in T helper cell differentiation. CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily. The CD86 protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory signal for act |
Immunogen | n/a |
Other Names | B7-2, B7.2, B70, CD28LG2, LAB72, MGC34413, B-lymphocyte activation antigen B7-2, B-lymphocyte antigen B7-2, B7-2 antigen, BU63, CD28 antigen ligand 2 |
Gene, Accession # | Entrez: 12524; Uniprot: P42082 |
Catalog # | 17-0862-81 |
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Order / More Info | CD86 (B7-2) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 18604213, 19237530, 19917700, 20068554, 20176793, 20427766, 20644175, 20844550, 20935647, 21540549, 21674051, 21685327, 22493545, 22590614, 23162549, 23300949, 23506849, 23527234, 23636062, 24253609, 24384074, 24554667, 24722202, 25289030, 25485616, 25548274, 25762540, 25975355, 26096149, 26109647, 26163371, 26265369, 26325217, 26436647, 26490642, 26624014, 26715642, 26833392, 26872029, 26986456, 26998006, 27216637, 27471636, 27761470, 27774091, 28018179, 28901417, 29163499, 29546785, 29670088, 29707136 |
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