| 产品详情 |
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| Antigenic Specificity | NDNL2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:25-1:100, Western Blot: 1:500-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NDNL2 Polyclonal Antibody. The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily. This is an intronless gene. Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). |
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| Immunogen | n/a |
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| Other Names | HCA4, MAGEG1, NDNL2 |
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| Gene, Accession # | Entrez: 56160, 66647; Uniprot: Q96MG7, Q9CPR8 |
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| Catalog # | PA5-50619 |
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| Price | |
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| Order / More Info | NDNL2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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