| 产品详情 |
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| Product Name | INDY |
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| Description | A DYRK1A inhibitor (Ki = 180 nM; IC50 = 240 nM); selective for DYRK1A over MAOA and B (100 µM); inhibits DYRK1A phosphorylation of tau in COS-7 cells expressing EGFP-DYRK1A and EGFP-tau in a concentration-dependent manner; induces proliferation of human and rat β-cells and increases insulin secretion by human islets in vitro; reverses developmental deformities induced by DYRK1A overexpression in X. laevis embryos, |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | DYRK-1A COS7 EGFPDYRK1A HEK-293 Xenopus MAOA MAOB |
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| Gene, Accession, CAS # | CAS: 1169755-45-6 |
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| Catalog # | 23895-25 |
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| Price | |
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| Order / More Info | INDY from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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