| 产品详情 |
| Edit |   |
|---|
| Product Name | Emricasan |
|---|
| Description | A pan-caspase inhibitor; prevents cold ischemia-warm reperfusion-induced SEC apoptosis and inhibits caspase-3 activation in rat liver at 10 mg/kg ex vivo; reduces ALT levels (ED50s = <0.01-0.38 mg/kg) as well as apoptosis and caspase activity in a dose-dependent manner in the α-Fas mouse and D-Gln/LPS rat models of liver injury; reduces caspase-3 and caspase-8 activity, serum ALT levels, hepatocyte apoptosis, and hepatic fibrogenesis in a mouse model of high-fat diet-induced NASH; enhances islet engraftment and lowers post-transplant fasting glucose levels in a porcine islet autotransplant model, |
|---|
| Size | 10 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | IDN-6556|PF-03491390 |
|---|
| Gene, Accession, CAS # | CAS: 254750-02-2 |
|---|
| Catalog # | 22204-10 |
|---|
| Price | |
|---|
| Order / More Info | Emricasan from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|