产品名称 Recombinant Lymphocytic choriomeningitis virus Pre-glycoprotein polyprotein GP complex (GPC), partial from BIOMATIK
产品货号 RPC20789
产品价格 现货询价,电话:010-67529703
产品规格 100ug
产品品牌 BIOMATIK
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Product NameRecombinant Lymphocytic choriomeningitis virus Pre-glycoprotein polyprotein GP complex (GPC), partial
DescriptionPurity > 90% as determined by SDS-PAGE. MW: 24.9kDa. Partial: 10-90aa. N-terminal 6xHis-SUMO-tagged. Lymphocytic choriomeningitis virus (strain Armstrong) (LCMV). Stable signal peptide (SSP) is cleaved but is apparently retained as the third component of the GP complex. The SSP is required for efficient glycoprotein expression, post-translational cleavage of GP1 and GP2, glycoprotein transport to the cell plasma membrane, formation of infectious virus particles, and acid pH-dependent glycoprotein-mediated cell fusion.1 Publication Glycoprotein G1 mediates virus attachment to host receptor alpha-dystroglycan DAG1. This attachment induces virion internalization predominantly through clathrin- and caveolin-independent endocytosis.1 Publication Glycoprotein G2 is a class I viral fusion protein, that directs fusion of viral and host endosomal membranes, leading to delivery of the nucleocapsid into the cytoplasm. Membrane fusion is mediated by irreversable conformational changes induced upon acidification in the endosome.
Size100ug
Concentrationn/a
ApplicationsRUO
Other Namesn/a
Gene, Accession, CAS #GPC, UniProt: P09991
Catalog #RPC20789
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Order / More InfoRecombinant Lymphocytic choriomeningitis virus Pre-glycoprotein polyprotein GP complex (GPC), partial from BIOMATIK
Product Specific Referencesn/a
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