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| Product Name | Recombinant Escherichia coli Antitoxin RelB (relB) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 16.1kDa. Full Length: 1-79aa. N-terminal 10xHis-tagged and C-terminal Myc-tagged. Escherichia coli (strain K12). Antitoxin component of a type II toxin-antitoxin (TA) system. Counteracts the effect of cognate toxin RelE via direct protein-protein interaction, preventing RelE from entering the ribosome A site and thus inhibiting its endoribonuclease activity. An autorepressor of relBE operon transcription. 2 RelB dimers bind to 2 operator sequences; DNA-binding and repression is stronger when complexed with toxin/corepressor RelE by conditional cooperativity. Increased transcription rate of relBE and activation of relE is consistent with a lower level of RelB in starved cells due to degradation of RelB by protease Lon. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | n/a |
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| Gene, Accession, CAS # | relB, UniProt: P0C079 |
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| Catalog # | RPC25670 |
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| Order / More Info | Recombinant Escherichia coli Antitoxin RelB (relB) from BIOMATIK |
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| Product Specific References | n/a |
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